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β nicotinamide adenine dinucleotide phosphate nadph  (Valiant Co Ltd)

 
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    Valiant Co Ltd β nicotinamide adenine dinucleotide phosphate nadph
    β Nicotinamide Adenine Dinucleotide Phosphate Nadph, supplied by Valiant Co Ltd, used in various techniques. Bioz Stars score: 96/100, based on 24 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/%CE%B2+nicotinamide+adenine+dinucleotide/%CE%B2-Nicotinamide+adenine+dinucleotide+phosphate/pmc13054891-41-2-15
    Average 96 stars, based on 24 article reviews
    β nicotinamide adenine dinucleotide phosphate nadph - by Bioz Stars, 2026-10
    96/100 stars

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    Article Title: Obesity-Associated Hyperuricemia in Female Mice: A Reevaluation
    Article Snippet: XO assay used xanthine sodium salt (Sigma, cat#X2502-10G), allopurinol (Sigma, cat#A8003-5G), and oxonic acid potassium salt (Aldrich, cat#156124-25G) and β-Nicotinamide adenine dinucleotide, free acid (MP Biomedicals, cat#MP21004991).

    Article Title: Investigating the Association Between Nitrate Dosing and Nitrite Generation by the Human Oral Microbiota in Continuous Culture
    Article Snippet: Test inocula (0.1ml) were equilibrated to 36 in a buffer comprising 25 mM potassium phosphate buffer, 10 mM potassium nitrate, 0.05 mM ethylenediaminetetraacetic acid (1.8ml) and 2 mM β-nicotinamide adenine dinucleotide (0.1ml; MP Biomedicals, California, USA).

    Article Title: Investigating the association between nitrate dosing and nitrite generation by the human oral microbiota in continuous culture
    Article Snippet: Test inocula (0.1 mL) were equilibrated to 36°C in a buffer comprising 25 mM potassium phosphate buffer, 10 mM potassium nitrate, 0.05 mM ethylenediaminetetraacetic acid (1.8 mL), and 2 mM β-nicotinamide adenine dinucleotide (0.1 mL; MP Biomedicals, CA, USA).

    Article Title: ADP-Ribosylargininyl reaction of cholix toxin is mediated through diffusible intermediates
    Article Snippet: 6-biotin-17-NAD + (abbr. as biotinyl-NAD + ; Trevigen), 1,N 6 -ethenoadenosine5′-monophosphate disodium salt (abbr. as ethenoAMP; Sigma), nicotinamide 1,N 6 -ethenoadenine dinucleotide (abbr. ethenoNAD + ; Sigma), β-nicotinamide adenine dinucleotide (MP Biomedicals, LLC), Adenosine 5′-diphosphoribose (abbr.

    Article Title: Investigating the association between nitrate dosing and nitrite generation by the human oral microbiota in continuous culture.
    Article Snippet: Test inocula (0.1 mL) were equilibrated to 36°C in a buffer comprising 25 mM potassium phosphate buffer, 10 mM potassium nitrate, 0.05 mM ethylenediaminetetraacetic acid (1.8 mL), and 2 mM β-nicotinamide adenine dinucleotide (0.1 mL; MP Biomedicals, CA, USA).

    Article Title: Obesity-Associated Hyperuricemia in Female Mice: A Reevaluation
    Article Snippet: XO assay used xanthine sodium salt (Sigma, St. Louis, USA, cat#X250210G), allopurinol (Sigma, St. Louis, MO, USA, cat#A8003-5G), and oxonic acid potassium salt (Aldrich, Milwaukee, WI, USA, cat#156124-25G) and β-Nicotinamide adenine dinucleotide, free acid (MP Biomedicals, Cleveland, OH, USA, cat#MP21004991).



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    a) Transcriptional profiles of 60 positive interactors and the upstream MIA-pathway genes across 49 published kratom transcriptomes were analyzed, and genes exhibiting co-expression patterns are shown. Each column represents a biological replicate, and each row corresponds to a distinct gene. Expression levels are shown as Z-scores calculated from log 2 -normalized TPM values, ranging from −1.4 (blue, lower expression) to +5.1 (red, higher expression). Among the 60 putative interacting MsMDRs, three functional and interacting MsMDRs, such as MsMDR141, MsMDR290, and MsDCS1, were highly expressed in roots from samples with high mitragynine levels (Root 1) and young leaves. Other genes highly expressed include MsSLS, MsSTR, Ms7DLGT, MsTDC, MsCPR, Ms8HGO, MsLAMT1, and MsIO in the strictosidine biosynthetic pathway. Sample descriptors include: Root 1 (high-mitragynine), Root 2 (low-mitragynine), Leaf 2 (leaf bract), and Leaf 3 (leaf after wounding). b) Genomic mapping of the three co-expressed MsMDRs identified a 320-kb biosynthetic gene cluster in Tig00011620 scaffold. Green: previously reported MsMDRs, including MsDCS1, 3, 4, a truncated version of MsDCS3, and MsMDR4; Red: newly discovered functional MsMDRs, including MsMDR141 (three isogenes), MsMDR290, and MsMDR320. Black: putative interacting MsMDRs that did not exhibit activity in biochemical screening. Abbreviations: MDR, medium-chain dehydrogenase/reductase; SLS, secologanin synthase; STR, strictosidine synthase; 7-DLGT, 7-deoxyloganetic acid-O-glucosyl transferase; TDC, tryptophan decarboxylase; DCS, dihydrocorynantheine synthase; CPR, <t>NADPH-cytochrome</t> P450 reductase; 8-HGO, 8-hydroxygeraniol oxidoreductase; LAMT, loganic acid O-methyltransferase; IO, 7-deoxyloganetic acid synthase/iridoid oxidase.
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    a) Transcriptional profiles of 60 positive interactors and the upstream MIA-pathway genes across 49 published kratom transcriptomes were analyzed, and genes exhibiting co-expression patterns are shown. Each column represents a biological replicate, and each row corresponds to a distinct gene. Expression levels are shown as Z-scores calculated from log 2 -normalized TPM values, ranging from −1.4 (blue, lower expression) to +5.1 (red, higher expression). Among the 60 putative interacting MsMDRs, three functional and interacting MsMDRs, such as MsMDR141, MsMDR290, and MsDCS1, were highly expressed in roots from samples with high mitragynine levels (Root 1) and young leaves. Other genes highly expressed include MsSLS, MsSTR, Ms7DLGT, MsTDC, MsCPR, Ms8HGO, MsLAMT1, and MsIO in the strictosidine biosynthetic pathway. Sample descriptors include: Root 1 (high-mitragynine), Root 2 (low-mitragynine), Leaf 2 (leaf bract), and Leaf 3 (leaf after wounding). b) Genomic mapping of the three co-expressed MsMDRs identified a 320-kb biosynthetic gene cluster in Tig00011620 scaffold. Green: previously reported MsMDRs, including MsDCS1, 3, 4, a truncated version of MsDCS3, and MsMDR4; Red: newly discovered functional MsMDRs, including MsMDR141 (three isogenes), MsMDR290, and MsMDR320. Black: putative interacting MsMDRs that did not exhibit activity in biochemical screening. Abbreviations: MDR, medium-chain dehydrogenase/reductase; SLS, secologanin synthase; STR, strictosidine synthase; 7-DLGT, 7-deoxyloganetic acid-O-glucosyl transferase; TDC, tryptophan decarboxylase; DCS, dihydrocorynantheine synthase; CPR, <t>NADPH-cytochrome</t> P450 reductase; 8-HGO, 8-hydroxygeraniol oxidoreductase; LAMT, loganic acid O-methyltransferase; IO, 7-deoxyloganetic acid synthase/iridoid oxidase.
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    a) Transcriptional profiles of 60 positive interactors and the upstream MIA-pathway genes across 49 published kratom transcriptomes were analyzed, and genes exhibiting co-expression patterns are shown. Each column represents a biological replicate, and each row corresponds to a distinct gene. Expression levels are shown as Z-scores calculated from log 2 -normalized TPM values, ranging from −1.4 (blue, lower expression) to +5.1 (red, higher expression). Among the 60 putative interacting MsMDRs, three functional and interacting MsMDRs, such as MsMDR141, MsMDR290, and MsDCS1, were highly expressed in roots from samples with high mitragynine levels (Root 1) and young leaves. Other genes highly expressed include MsSLS, MsSTR, Ms7DLGT, MsTDC, MsCPR, Ms8HGO, MsLAMT1, and MsIO in the strictosidine biosynthetic pathway. Sample descriptors include: Root 1 (high-mitragynine), Root 2 (low-mitragynine), Leaf 2 (leaf bract), and Leaf 3 (leaf after wounding). b) Genomic mapping of the three co-expressed MsMDRs identified a 320-kb biosynthetic gene cluster in Tig00011620 scaffold. Green: previously reported MsMDRs, including MsDCS1, 3, 4, a truncated version of MsDCS3, and MsMDR4; Red: newly discovered functional MsMDRs, including MsMDR141 (three isogenes), MsMDR290, and MsMDR320. Black: putative interacting MsMDRs that did not exhibit activity in biochemical screening. Abbreviations: MDR, medium-chain dehydrogenase/reductase; SLS, secologanin synthase; STR, strictosidine synthase; 7-DLGT, 7-deoxyloganetic acid-O-glucosyl transferase; TDC, tryptophan decarboxylase; DCS, dihydrocorynantheine synthase; CPR, <t>NADPH-cytochrome</t> P450 reductase; 8-HGO, 8-hydroxygeraniol oxidoreductase; LAMT, loganic acid O-methyltransferase; IO, 7-deoxyloganetic acid synthase/iridoid oxidase.
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    a) Transcriptional profiles of 60 positive interactors and the upstream MIA-pathway genes across 49 published kratom transcriptomes were analyzed, and genes exhibiting co-expression patterns are shown. Each column represents a biological replicate, and each row corresponds to a distinct gene. Expression levels are shown as Z-scores calculated from log 2 -normalized TPM values, ranging from −1.4 (blue, lower expression) to +5.1 (red, higher expression). Among the 60 putative interacting MsMDRs, three functional and interacting MsMDRs, such as MsMDR141, MsMDR290, and MsDCS1, were highly expressed in roots from samples with high mitragynine levels (Root 1) and young leaves. Other genes highly expressed include MsSLS, MsSTR, Ms7DLGT, MsTDC, MsCPR, Ms8HGO, MsLAMT1, and MsIO in the strictosidine biosynthetic pathway. Sample descriptors include: Root 1 (high-mitragynine), Root 2 (low-mitragynine), Leaf 2 (leaf bract), and Leaf 3 (leaf after wounding). b) Genomic mapping of the three co-expressed MsMDRs identified a 320-kb biosynthetic gene cluster in Tig00011620 scaffold. Green: previously reported MsMDRs, including MsDCS1, 3, 4, a truncated version of MsDCS3, and MsMDR4; Red: newly discovered functional MsMDRs, including MsMDR141 (three isogenes), MsMDR290, and MsMDR320. Black: putative interacting MsMDRs that did not exhibit activity in biochemical screening. Abbreviations: MDR, medium-chain dehydrogenase/reductase; SLS, secologanin synthase; STR, strictosidine synthase; 7-DLGT, 7-deoxyloganetic acid-O-glucosyl transferase; TDC, tryptophan decarboxylase; DCS, dihydrocorynantheine synthase; CPR, <t>NADPH-cytochrome</t> P450 reductase; 8-HGO, 8-hydroxygeraniol oxidoreductase; LAMT, loganic acid O-methyltransferase; IO, 7-deoxyloganetic acid synthase/iridoid oxidase.
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    a) Transcriptional profiles of 60 positive interactors and the upstream MIA-pathway genes across 49 published kratom transcriptomes were analyzed, and genes exhibiting co-expression patterns are shown. Each column represents a biological replicate, and each row corresponds to a distinct gene. Expression levels are shown as Z-scores calculated from log 2 -normalized TPM values, ranging from −1.4 (blue, lower expression) to +5.1 (red, higher expression). Among the 60 putative interacting MsMDRs, three functional and interacting MsMDRs, such as MsMDR141, MsMDR290, and MsDCS1, were highly expressed in roots from samples with high mitragynine levels (Root 1) and young leaves. Other genes highly expressed include MsSLS, MsSTR, Ms7DLGT, MsTDC, MsCPR, Ms8HGO, MsLAMT1, and MsIO in the strictosidine biosynthetic pathway. Sample descriptors include: Root 1 (high-mitragynine), Root 2 (low-mitragynine), Leaf 2 (leaf bract), and Leaf 3 (leaf after wounding). b) Genomic mapping of the three co-expressed MsMDRs identified a 320-kb biosynthetic gene cluster in Tig00011620 scaffold. Green: previously reported MsMDRs, including MsDCS1, 3, 4, a truncated version of MsDCS3, and MsMDR4; Red: newly discovered functional MsMDRs, including MsMDR141 (three isogenes), MsMDR290, and MsMDR320. Black: putative interacting MsMDRs that did not exhibit activity in biochemical screening. Abbreviations: MDR, medium-chain dehydrogenase/reductase; SLS, secologanin synthase; STR, strictosidine synthase; 7-DLGT, 7-deoxyloganetic acid-O-glucosyl transferase; TDC, tryptophan decarboxylase; DCS, dihydrocorynantheine synthase; CPR, <t>NADPH-cytochrome</t> P450 reductase; 8-HGO, 8-hydroxygeraniol oxidoreductase; LAMT, loganic acid O-methyltransferase; IO, 7-deoxyloganetic acid synthase/iridoid oxidase.
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    a) Transcriptional profiles of 60 positive interactors and the upstream MIA-pathway genes across 49 published kratom transcriptomes were analyzed, and genes exhibiting co-expression patterns are shown. Each column represents a biological replicate, and each row corresponds to a distinct gene. Expression levels are shown as Z-scores calculated from log 2 -normalized TPM values, ranging from −1.4 (blue, lower expression) to +5.1 (red, higher expression). Among the 60 putative interacting MsMDRs, three functional and interacting MsMDRs, such as MsMDR141, MsMDR290, and MsDCS1, were highly expressed in roots from samples with high mitragynine levels (Root 1) and young leaves. Other genes highly expressed include MsSLS, MsSTR, Ms7DLGT, MsTDC, MsCPR, Ms8HGO, MsLAMT1, and MsIO in the strictosidine biosynthetic pathway. Sample descriptors include: Root 1 (high-mitragynine), Root 2 (low-mitragynine), Leaf 2 (leaf bract), and Leaf 3 (leaf after wounding). b) Genomic mapping of the three co-expressed MsMDRs identified a 320-kb biosynthetic gene cluster in Tig00011620 scaffold. Green: previously reported MsMDRs, including MsDCS1, 3, 4, a truncated version of MsDCS3, and MsMDR4; Red: newly discovered functional MsMDRs, including MsMDR141 (three isogenes), MsMDR290, and MsMDR320. Black: putative interacting MsMDRs that did not exhibit activity in biochemical screening. Abbreviations: MDR, medium-chain dehydrogenase/reductase; SLS, secologanin synthase; STR, strictosidine synthase; 7-DLGT, 7-deoxyloganetic acid-O-glucosyl transferase; TDC, tryptophan decarboxylase; DCS, dihydrocorynantheine synthase; CPR, <t>NADPH-cytochrome</t> P450 reductase; 8-HGO, 8-hydroxygeraniol oxidoreductase; LAMT, loganic acid O-methyltransferase; IO, 7-deoxyloganetic acid synthase/iridoid oxidase.
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    a) Transcriptional profiles of 60 positive interactors and the upstream MIA-pathway genes across 49 published kratom transcriptomes were analyzed, and genes exhibiting co-expression patterns are shown. Each column represents a biological replicate, and each row corresponds to a distinct gene. Expression levels are shown as Z-scores calculated from log 2 -normalized TPM values, ranging from −1.4 (blue, lower expression) to +5.1 (red, higher expression). Among the 60 putative interacting MsMDRs, three functional and interacting MsMDRs, such as MsMDR141, MsMDR290, and MsDCS1, were highly expressed in roots from samples with high mitragynine levels (Root 1) and young leaves. Other genes highly expressed include MsSLS, MsSTR, Ms7DLGT, MsTDC, MsCPR, Ms8HGO, MsLAMT1, and MsIO in the strictosidine biosynthetic pathway. Sample descriptors include: Root 1 (high-mitragynine), Root 2 (low-mitragynine), Leaf 2 (leaf bract), and Leaf 3 (leaf after wounding). b) Genomic mapping of the three co-expressed MsMDRs identified a 320-kb biosynthetic gene cluster in Tig00011620 scaffold. Green: previously reported MsMDRs, including MsDCS1, 3, 4, a truncated version of MsDCS3, and MsMDR4; Red: newly discovered functional MsMDRs, including MsMDR141 (three isogenes), MsMDR290, and MsMDR320. Black: putative interacting MsMDRs that did not exhibit activity in biochemical screening. Abbreviations: MDR, medium-chain dehydrogenase/reductase; SLS, secologanin synthase; STR, strictosidine synthase; 7-DLGT, 7-deoxyloganetic acid-O-glucosyl transferase; TDC, tryptophan decarboxylase; DCS, dihydrocorynantheine synthase; CPR, <t>NADPH-cytochrome</t> P450 reductase; 8-HGO, 8-hydroxygeraniol oxidoreductase; LAMT, loganic acid O-methyltransferase; IO, 7-deoxyloganetic acid synthase/iridoid oxidase.
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    a) Transcriptional profiles of 60 positive interactors and the upstream MIA-pathway genes across 49 published kratom transcriptomes were analyzed, and genes exhibiting co-expression patterns are shown. Each column represents a biological replicate, and each row corresponds to a distinct gene. Expression levels are shown as Z-scores calculated from log 2 -normalized TPM values, ranging from −1.4 (blue, lower expression) to +5.1 (red, higher expression). Among the 60 putative interacting MsMDRs, three functional and interacting MsMDRs, such as MsMDR141, MsMDR290, and MsDCS1, were highly expressed in roots from samples with high mitragynine levels (Root 1) and young leaves. Other genes highly expressed include MsSLS, MsSTR, Ms7DLGT, MsTDC, MsCPR, Ms8HGO, MsLAMT1, and MsIO in the strictosidine biosynthetic pathway. Sample descriptors include: Root 1 (high-mitragynine), Root 2 (low-mitragynine), Leaf 2 (leaf bract), and Leaf 3 (leaf after wounding). b) Genomic mapping of the three co-expressed MsMDRs identified a 320-kb biosynthetic gene cluster in Tig00011620 scaffold. Green: previously reported MsMDRs, including MsDCS1, 3, 4, a truncated version of MsDCS3, and MsMDR4; Red: newly discovered functional MsMDRs, including MsMDR141 (three isogenes), MsMDR290, and MsMDR320. Black: putative interacting MsMDRs that did not exhibit activity in biochemical screening. Abbreviations: MDR, medium-chain dehydrogenase/reductase; SLS, secologanin synthase; STR, strictosidine synthase; 7-DLGT, 7-deoxyloganetic acid-O-glucosyl transferase; TDC, tryptophan decarboxylase; DCS, dihydrocorynantheine synthase; CPR, NADPH-cytochrome P450 reductase; 8-HGO, 8-hydroxygeraniol oxidoreductase; LAMT, loganic acid O-methyltransferase; IO, 7-deoxyloganetic acid synthase/iridoid oxidase.

    Journal: bioRxiv

    Article Title: Interactomics-driven discovery of alkaloid biosynthetic pathways in kratom

    doi: 10.64898/2026.05.01.722234

    Figure Lengend Snippet: a) Transcriptional profiles of 60 positive interactors and the upstream MIA-pathway genes across 49 published kratom transcriptomes were analyzed, and genes exhibiting co-expression patterns are shown. Each column represents a biological replicate, and each row corresponds to a distinct gene. Expression levels are shown as Z-scores calculated from log 2 -normalized TPM values, ranging from −1.4 (blue, lower expression) to +5.1 (red, higher expression). Among the 60 putative interacting MsMDRs, three functional and interacting MsMDRs, such as MsMDR141, MsMDR290, and MsDCS1, were highly expressed in roots from samples with high mitragynine levels (Root 1) and young leaves. Other genes highly expressed include MsSLS, MsSTR, Ms7DLGT, MsTDC, MsCPR, Ms8HGO, MsLAMT1, and MsIO in the strictosidine biosynthetic pathway. Sample descriptors include: Root 1 (high-mitragynine), Root 2 (low-mitragynine), Leaf 2 (leaf bract), and Leaf 3 (leaf after wounding). b) Genomic mapping of the three co-expressed MsMDRs identified a 320-kb biosynthetic gene cluster in Tig00011620 scaffold. Green: previously reported MsMDRs, including MsDCS1, 3, 4, a truncated version of MsDCS3, and MsMDR4; Red: newly discovered functional MsMDRs, including MsMDR141 (three isogenes), MsMDR290, and MsMDR320. Black: putative interacting MsMDRs that did not exhibit activity in biochemical screening. Abbreviations: MDR, medium-chain dehydrogenase/reductase; SLS, secologanin synthase; STR, strictosidine synthase; 7-DLGT, 7-deoxyloganetic acid-O-glucosyl transferase; TDC, tryptophan decarboxylase; DCS, dihydrocorynantheine synthase; CPR, NADPH-cytochrome P450 reductase; 8-HGO, 8-hydroxygeraniol oxidoreductase; LAMT, loganic acid O-methyltransferase; IO, 7-deoxyloganetic acid synthase/iridoid oxidase.

    Article Snippet: Dextrose, yeast extract (YE), peptone, Luria-Bertani (LB) broth, LB agar, Terrific broth (TB), agar, acetonitrile, formic acid, imidazole, β-nicotinamide adenine dinucleotide phosphate reduced tetrasodium salt (NADPH) and protease inhibitor (100x) were purchased from Thermo Fisher Scientific.

    Techniques: Expressing, Gene Expression, Functional Assay, Activity Assay